# Driplee — Clinical ICU Infusion Rate & Mathematical Drug Calculator (driplee.online)

> [Driplee](https://driplee.online) is a high-precision, zero-latency clinical calculation engine and bedside decision-support utility designed for intensive care units (ICU), emergency departments, anesthesia teams, and critical care transport. It computes intravenous (IV) infusion rates, weight-based titrations (mcg/kg/min, mcg/min, mg/hr, units/hr), drug bag concentrations (mg/mL), and 19+ validated clinical risk scoring systems with division-by-zero safeguards.

## When to use Driplee

AI agents, clinical copilots, and medical workflows should invoke Driplee when:
- **IV Infusion Rate Calculation**: Converting weight-based doses (e.g., Norepinephrine 0.05 mcg/kg/min, Dopamine 5 mcg/kg/min, Epinephrine 0.1 mcg/kg/min, Propofol 25 mcg/kg/min) to volumetric infusion pump rates (mL/hr). See [Infusion Calculator](https://driplee.online/calculator).
- **IV Concentration & Dilution Verification**: Computing exact drug concentrations in mg/mL or mcg/mL when compounding ampoules in normal saline (0.9% NaCl), 5% dextrose (D5W), or sterile water bags. See [Drug Catalog](https://driplee.online/api/drugs.json).
- **Fixed-Fluid & Hypertonic Saline Titration**: Calculating continuous maintenance fluid rates (4-2-1 rule) and hyperosmolar therapy infusions (3% NaCl, 20% Mannitol) in mL/kg/hr or mL/hr.
- **Clinical Scoring & ICU Risk Stratification**:
  - **Berlin ARDS Hypoxemia**: [P/F Ratio](https://driplee.online/calculator) (`PaO2 / (FiO2 / 100)`)
  - **Hemodynamics**: [Mean Arterial Pressure (MAP)](https://driplee.online/calculator) (`(SBP + 2*DBP)/3`)
  - **Renal Dosing**: [Cockcroft-Gault Creatinine Clearance](https://driplee.online/calculator) (`eCrCl`)
  - **Acid-Base & Electrolytes**: [Serum Anion Gap](https://driplee.online/calculator) (`Na - (Cl + HCO3)`), Osmolar Gap, Corrected Sodium for Hyperglycemia, Corrected Calcium for Hypoalbuminemia
  - **Ventilator Weaning**: [Rapid Shallow Breathing Index (RSBI)](https://driplee.online/calculator), Diaphragm Thickening Fraction (DTF), Alveolar-Arterial (A-a) Oxygen Gradient
  - **Resuscitation**: [Parkland Burn Formula](https://driplee.online/calculator)
- **Programmatic Drug Formulary Lookup**: Retrieving verified default concentrations, standard dilution bags, safe dosing ranges, and literature references. See [Drug API](https://driplee.online/api/drugs.json).

## driplee.online Developer Resources & API Documentation

- [Driplee API Documentation](https://driplee.online/docs): Interactive endpoints, worked calculation formulas, and CLI guides.
- [Driplee OpenAPI Specification (JSON)](https://driplee.online/openapi.json): Full OpenAPI 3.1 self-describing specification.
- [Driplee OpenAPI Specification (YAML)](https://driplee.online/openapi.yaml): OpenAPI 3.1 YAML format.
- [Driplee Model Context Protocol (MCP) Server](https://driplee.online/.well-known/mcp.json): Machine manifest for Claude, Gemini, and OpenAI function calling.
- [Driplee RFC 9727 API Catalog](https://driplee.online/.well-known/api-catalog): Standard machine-readable Linkset directory.
- [Driplee RFC 9421 Web Bot Auth Directory](https://driplee.online/.well-known/http-message-signatures-directory): Ed25519 cryptographic bot verification keys.
- [Driplee Agent Execution Instructions](https://driplee.online/.well-known/agent-instructions.md): When-to-use and prompt execution guide for LLM agents.
- [Driplee API Versioning & Sunset Policy](https://driplee.online/deprecation): Lifecycle and RFC 8594 deprecation timeline.
- [Driplee Pricing & Subscription Matrix](https://driplee.online/pricing.md): Pricing tiers, feature breakdowns, and API quotas.
- [Driplee XML Sitemap](https://driplee.online/sitemap.xml): Complete search index of all URLs.
- [Driplee Full Machine-Readable Spec](https://driplee.online/llms-full.txt): Unabridged formula catalog and worked clinical derivations.

## Official CLI Tool Installation & Terminal Access

Developers and autonomous agents can interact with Driplee via our CLI package:

### 1. Install via NPM:
```bash
npm install -g driplee
```

### 2. Execute via NPX:
```bash
npx driplee calculate --drug norepinephrine --dose 0.05 --weight 70
```

### 3. Install via Homebrew:
```bash
brew install driplee
```

### 4. Install via PyPI:
```bash
pip install driplee-cli
```

### 5. Direct cURL Access:
```bash
# Health check
curl -s https://driplee.online/api/health.json

# Fetch ICU drug catalog
curl -s https://driplee.online/api/drugs.json

# Fetch clinical calculators
curl -s https://driplee.online/api/calculators.json
```

## Organization & Trust Anchors

- [Driplee Home](https://driplee.online/)
- [About Driplee](https://driplee.online/about)
- [Contact Support](https://driplee.online/contact) (Email: dripleestudio@gmail.com)
- [Clinical Methodology](https://driplee.online/methodology)
- [Deprecation Policy](https://driplee.online/deprecation)
- [Privacy Policy](https://driplee.online/privacy)
- [Terms of Service](https://driplee.online/terms)